After six years of peace, François 1st, who wants to take again the Milanese, renews his alliance with England and the Turks, and finds new allies in the Protestant princes of Germany.
This third war is undecided.
François 1st invades Piedmont, but is rejected in France; Charles-Quint invades Provence, but is rejected in Italy (1536).
The pope, frightened power of the Turks, decides the two rivals to conclude the truce from Nice (1538).
After four years of peace, during which the two enemies seem entirely reconciled, François 1st, who does not draw any advantage from his alliance with Charles-Quint, starts again the fight with the assistance of the Turks (1542), but Henri VIII turns himself against him (1543).
This fourth war finishes with the advantage of France: the Turks devastate Hungary, and a French Army gains a great victory with Cérisoles in Piedmont (1544); Charles-Quint invades Champagne, but frightened progress of the Protestants, it signs the treaty of Crespy, by which it promises the Milanese in France (1544); Henri VIII, remained only, sign in its turn the treaty of Ardres, by which it promises to return Boulogne against a ransom (1546).
François 1st dies the following year: during its reign, France glorieusement fought against the house of Austria.
A the interior, the royalty became absolute.